SHIP Is Required for Dendritic Cell Maturation
نویسندگان
چکیده
منابع مشابه
SHIP is required for dendritic cell maturation.
Although several groups have investigated the role of SHIP in macrophage (M) development and function, SHIP's contribution to the generation, maturation, and innate immune activation of dendritic cells (DCs) is poorly understood. We show herein that SHIP negatively regulates the generation of DCs from bone marrow precursors in vitro and in vivo, as illustrated by the enhanced expansion of DCs f...
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*Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 723 Light Hall, Nashville, TN 37232; †Centre d’Immunologie de Marseille-Luminy, Centre National de la Recherche Scientifique–Institut National de la Santé et de la Recherche Médicale–Universite Mediterrane, Campus de Luminy, Case 906, 13288 Marseille Cedex 09, France; and ‡Samuel Lunenfeld Research Institu...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2010
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.0903170